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No other significant developmental toxicities (malformations and embryo-fetal lethality) were observed up to the highest dose tested, 1,000 mg/kg/day. No developmental effects were observed in rabbits at 300 mg/kg/day resulting in systemic exposure (AUC24) approximately 3 times higher than clinical exposures at the approved human dose of PAXLOVID. A pre- and postnatal developmental (PPND) study in pregnant rats administered oral nirmatrelvir doses of up to 1,000 mg/kg/day from GD 6 through Lactation Day (LD) 20 showed no adverse findings. No significant differences in offspring body weight were observed from PND 28 to PND 56.

If you experience sudden decrease or loss of vision or your vision is distorted, dimmed while you are taking CIALIS, stop taking CIALIS and contact your doctor immediately. It is important to tell your doctor about any heart problems you have now or may have had in the past. This medicine can cause serious side effects in patients with heart problems.

However, if you take sildenafil with a high-fat meal, it will take longer for the medication to start to work. When patients come to us looking for relief from their erectile dysfunction, they are faced with a preliminary decision of which medication, tadalafil or sildenafil, is better. Back in the day, Viagra 50 mg when these medications were still on patent AND named Cialis and Viagra 50 mg, respectively, they were very costly.

Studies have shown the drug tadalafil and its trade name Cialis to have a success rate of 60-70% in treating ED. ED is one of the most common and also least discussed medical conditions suffered by men. If you’re taking Cialis as needed, remember to give it enough time to work.

They will advise you on whether it's safe for you to use Cialis with your medications, and how to take your medications safely. Cialis interacts with a&nbsp